By public transit, exit at Waterfront Station. The SFU Harbour Centre is located directly across the street; enter from West Hastings Street.
"Simon Fraser University's downtown campus blends history with high tech in state-of-the-art education facilities in some of Vancouver's best-known landmarks.
Creation of the downtown campus was a 10-year project. The university had pioneered university mid-career professional education in Vancouver in the early 1980s with the launch of a store-front centre. It was rapidly outgrown and larger premises were leased. Dr. Warren Gill, SFU’s vice-president, university relations and an urban geographer who has played a key role in the development of SFU’s downtown presence says "It was clear there was need for a downtown university centre, but Simon Fraser knew it had to establish the facility through private sector support." This was achieved and the re-built and revitalized 1927 Spencer building officially opened as SFU’s Vancouver campus on May 5, 1989."
from:
http://www.harbour.sfu.ca/about/index.html